Can a single medication truly transform one’s weight, health, and overall well-being? The introduction of Zepbound, an FDA-approved prescription drug, suggests a resounding yes. This innovative treatment has the potential to revolutionize the way we approach chronic weight management, offering a glimmer of hope for millions struggling with obesity and its associated conditions1.
Zepbound, also known as tirzepatide, is an injectable medication that has been approved by the FDA for use in adults with obesity (BMI of 30 kg/m2 or greater) or overweight (BMI of 27 kg/m2 or greater) who also have at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol1.
Key Takeaways:
- Zepbound is an FDA-approved prescription medication for chronic weight management in adults with obesity or overweight and at least one weight-related condition.
- In clinical trials, Zepbound has demonstrated significant weight loss results when combined with a reduced-calorie diet and increased physical activity.
- Zepbound can lead to an average weight loss of up to 20.9% (48 lbs) in adults without diabetes and 14.7% (33 lbs) in adults with diabetes.
- Zepbound should not be used in patients with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2.
- Successful weight loss with Zepbound requires a holistic approach, including diet, lifestyle changes, and long-term commitment to healthier habits.
What is Zepbound?
Zepbound, also known as tirzepatide, is an injectable prescription medication that has been approved by the2 the U.S. Food and Drug Administration (FDA) for the treatment of chronic weight management in adults with obesity (BMI of 30 kg/m2 or greater) or overweight (BMI of 27 kg/m2 or greater) with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol3. Zepbound is indicated for use in combination with a reduced-calorie diet and increased physical activity.
Zepbound is noted to lead to at least a 22% total body weight loss at 72 weeks compared to 15% for Wegovy at 68 weeks2. In a double-blind, randomized, controlled trial, the highest dose of tirzepatide (15 milligrams) resulted in a 22.5% reduction in weight over 72 weeks2. Another trial showed participants receiving tirzepatide had a weight loss of 26.6% compared to 3.8% for those on placebo after an intensive lifestyle intervention for weight loss2.
Zepbound Dosage and Administration
Zepbound comes in six strengths in milligrams per 0.5 milliliters (mg/mL): 2.5, 5, 7.5, 10, 12.5, and 153. The typical starting dose for Zepbound is 2.5 mg per week for 4 weeks, which can increase to a maximum of 15 mg once per week3. Zepbound is meant to be a long-term treatment3.
The list price for Zepbound from Eli Lilly is $1,059.87, with potential savings available through a savings card program soon to be launched on the Zepbound website2. Zepbound might be covered by insurance for some patients, with the possibility of being eligible to pay as low as $25 for a one-month or three-month supply with a Zepbound savings card2.
Zepbound is advised for chronic weight management in adults with obesity or overweight alongside a reduced-calorie diet and increased physical activity2. Potential side effects of Zepbound include diarrhea, nausea, vomiting, constipation, injection site reactions, fatigue, allergic reactions, hair loss, and gastroesophageal reflux disease234.
How Does Zepbound Work?
Zepbound, the prescription weight loss medication, works by mimicking the actions of two naturally occurring hormones in the body – GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide, also known as gastric inhibitory polypeptide)5. By activating these hormone receptors, Zepbound helps regulate glucose and lipid metabolism, slowing down the rate of gastric emptying to make patients feel fuller for longer and ultimately leading to weight loss for individuals struggling with chronic obesity56.
The dual agonistic effect of Zepbound on GLP-1 and GIP receptors is what sets it apart from other weight loss medications that target only one of these hormones6. This unique mechanism of action allows Zepbound to effectively manage glucose levels, suppress appetite, and promote weight loss in a more comprehensive manner.
During clinical trials, Zepbound has demonstrated significant weight loss results when combined with a reduced-calorie diet and increased physical activity5. Patients using the highest approved dose of Zepbound (15 mg once weekly) have lost up to 21% of their body weight, with some experiencing an average reduction of 18% in their body weight56.
https://www.youtube.com/watch?v=5ZjQqeBQFgg
Zepbound, along with other weight loss medications in the same class, typically have a high price tag, exceeding $1,000 per month5. However, the potential benefits of significant and sustained weight loss, improved metabolic health, and reduced obesity-related complications make Zepbound an attractive option for many individuals seeking a comprehensive weight management solution.
| Zepbound Dosage and Weight Loss Outcomes | Weight Loss Percentage |
|---|---|
| Highest approved dose (15 mg once weekly) | Up to 21% body weight lost6 |
| Average weight loss in clinical trials | 18% body weight lost56 |
| Weight loss for individuals with diabetes | 12% body weight lost5 |
It’s important to note that Zepbound, like other injectable weight loss medications, needs to be used on a weekly basis5. Additionally, Zepbound is specifically FDA-approved for adults aged 18 and older with a BMI of 30 or higher for obesity, or a BMI of 27 or greater with additional weight-related health concerns6.
By leveraging the powerful mechanisms of GLP-1 and GIP, Zepbound offers a promising solution for individuals struggling with chronic obesity and weight-related health issues. However, it’s crucial to weigh the potential benefits against the risks and costs associated with this medication, and to always consult with a healthcare provider before starting any new weight loss regimen567.
Zepbound’s Effectiveness for Weight Loss
The effectiveness of Zepbound for chronic weight management has been well-established in clinical trials8. Nearly 42% of Americans are obese according to the CDC, making Zepbound a potentially transformative solution for those struggling with excess weight8. In clinical trials, Zepbound has demonstrated significant weight loss results when combined with a reduced-calorie diet and increased physical activity.
In the larger SURMOUNT-3 trial, participants who took the highest approved dose of Zepbound (15 mg once weekly) lost an impressive 18.4% of their initial body weight on average, compared to just 2.5% for the placebo group8. The SURMOUNT-4 trial further reinforced Zepbound’s efficacy, with participants who took the medication throughout the entire 88 weeks experiencing a remarkable 25.3% reduction in body weight, while those who switched to placebo averaged a 9.9% loss8.
Zepbound’s weight loss results are nearly comparable to those achieved through bariatric surgery9. In clinical trials, Zepbound helped people lose an average of 52 pounds, with a 15 mg dose leading to a 22.5% body weight reduction, equivalent to about 52 pounds9. Even at the lower 10 mg and 5 mg doses, participants experienced average weight losses of 48 pounds and 35 pounds, respectively9.
The impressive weight loss achieved with Zepbound is further highlighted by the fact that 87.5% of participants taking the medication in the SURMOUNT-3 trial achieved an additional weight reduction of up to 5%, compared to just 16.5% in the placebo group8. Additionally, 89.5% of participants who continued receiving Zepbound in the SURMOUNT-4 trial were able to maintain at least 80% of their weight loss, a stark contrast to the 16.6% in the placebo group8.
The FDA’s approval of Zepbound for chronic weight management in adults with obesity or overweight and at least one weight-related condition underscores the medication’s effectiveness10. With its potential to deliver significant and sustained weight loss, Zepbound offers a promising solution for those seeking to improve their overall health and well-being8910.
Zepbound Dosage and Administration
Zepbound, also known as tirzepatide, is an injectable prescription medication approved by the FDA for chronic weight management in adults with obesity or overweight with at least one weight-related condition11. To achieve the desired weight loss results, the dosage of Zepbound must be carefully titrated and administered according to the recommended guidelines11.
Zepbound comes in six strengths: 2.5 mg/0.5 mL, 5 mg/0.5 mL, 7.5 mg/0.5 mL, 10 mg/0.5 mL, 12.5 mg/0.5 mL, and 15 mg/0.5 mL11. The typical recommended dosage of Zepbound to help manage weight is 5 mg, 10 mg, or 15 mg once per week11. After 4 weeks, the dosage of Zepbound may be increased to 5 mg once per week, with further increases of 2.5 mg once every 4 weeks, reaching a maximum dose of 15 mg once per week11.
Zepbound is meant to be a long-term treatment for weight management, and the dosage prescribed depends on factors such as individual response to the drug, other medications being taken, side effects experienced, and other medical conditions present11. The drug should be taken along with dietary and exercise changes for effective weight management11.
Zepbound is administered as a subcutaneous injection in the stomach, thigh, or upper arm once per week11. If a dose of Zepbound is missed, it can be taken within 4 days (96 hours) of the missed dose; otherwise, the next dose should be taken as scheduled11. Taking more than the prescribed amount of Zepbound can lead to harmful effects or overdose; in such cases, medical assistance should be sought immediately11.
| Zepbound Dosage | Typical Recommended Dose | Maximum Dose | Dose Escalation |
|---|---|---|---|
| 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg | 5 mg, 10 mg, or 15 mg once per week | 15 mg once per week | Increase by 2.5 mg every 4 weeks to reach maximum |
It’s important to note that Zepbound is intended for long-term use and should be taken as directed by a healthcare provider to ensure the best possible weight loss results and safety12. Proper storage, handling, and disposal of Zepbound pens are also crucial to maintain the integrity of the medication and prevent potential safety risks12.
In summary, the Zepbound dosage and administration regimen is designed to gradually increase the dose over several weeks to reach the target maintenance dose, which can range from 5 mg to 15 mg once weekly13. Careful adherence to the prescribed dosing schedule and any additional instructions from the healthcare provider is essential for achieving the desired weight loss outcomes with Zepbound13.
Weight Loss Results from Clinical Trials
Clinical trials have demonstrated the remarkable weight reduction potential of Zepbound, the FDA-approved prescription medication for chronic weight management. In a trial involving over 2,500 adults without diabetes, participants who received the highest approved dosage of Zepbound (15 mg once weekly) lost an impressive 18% of their body weight on average, compared to those who received a placebo14.
These findings are consistent with other clinical studies, where Zepbound has been shown to deliver significant and sustained weight loss results. For instance, in the SURMOUNT-4 trial, participants on Zepbound experienced a mean weight reduction of 20.9% after 36 weeks of open-label treatment, and maintained an impressive 93.4% of their weight loss at 88 weeks15.
The weight loss benefits of Zepbound go beyond just the initial reduction in body weight. Studies have revealed that Zepbound can help individuals maintain their weight loss over the long term. Participants in the SURMOUNT-4 trial who transitioned from Zepbound to a placebo experienced a modest 14% weight regain approximately one year later, suggesting that Zepbound may have a lasting impact on weight management16.
These clinical trial results underscore the efficacy of Zepbound as a valuable tool in the fight against obesity and overweight conditions. By combining Zepbound with a reduced-calorie diet and increased physical activity, adults without diabetes can achieve substantial and sustainable weight loss, potentially improving their overall health and well-being14.
It’s important to note that individual results may vary, and patients should always consult with their healthcare providers to determine the most appropriate treatment plan. Nonetheless, the compelling evidence from clinical trials underscores the promising role of Zepbound in the management of weight-related conditions15.
Weight Loss on Zepbound for Individuals with Diabetes
The weight loss benefits of Zepbound (tirzepatide) have been particularly impressive for individuals living with type 2 diabetes. In a clinical trial involving 958 adults with type 2 diabetes, those who received the highest approved dosage of Zepbound (15 mg once weekly) lost an average of 12% of their body weight compared to those who received a placebo17. At the start of this trial, the average body weight was 222 pounds (101 kg) and the average BMI was 36 kg/m².
The study found that Zepbound was effective for weight loss regardless of the number of obesity-related medical conditions a person had18. This is significant, as many individuals with type 2 diabetes also struggle with other weight-related health issues. The findings indicate that Zepbound can be a valuable tool in managing both diabetes and excess weight for this patient population.
Similar to the results seen in clinical trials for adults without diabetes, Zepbound has demonstrated impressive long-term weight loss for those with type 2 diabetes. Patients who continued Zepbound treatment for an additional year after the initial 52-week study lost another 5.5% of their weight, totaling a 25% weight loss19. However, participants who switched to a placebo after the initial year regained 14% of their weight, underscoring the need for ongoing Zepbound treatment to maintain the weight loss benefits.
The weight loss achieved with Zepbound in individuals with type 2 diabetes has also been accompanied by significant improvements in other health markers, such as BMI, lipid levels, diabetes indicators, and blood pressure19. These findings highlight the potential of Zepbound to provide a comprehensive approach to managing both weight and diabetes-related complications for this patient population.
Overall, the clinical trial data suggest that Zepbound can be an effective and valuable option for adults with type 2 diabetes who are struggling with excess weight and obesity-related health issues. By addressing the underlying metabolic factors that contribute to both conditions, Zepbound offers a promising solution for this high-risk group18.
Zepbound’s Safety Profile
Zepbound, the revolutionary weight loss medication, has been extensively studied for its safety and efficacy. While this injectable prescription drug can be an effective tool for chronic weight management, it’s crucial to be aware of its potential side effects20.
The most commonly reported side effects of Zepbound include nausea, diarrhea, vomiting, constipation, abdominal discomfort and pain, injection site reactions, fatigue, hypersensitivity reactions, burping, hair loss, and gastroesophageal reflux disease20. More severe side effects may include kidney problems, gallbladder issues, allergic reactions, low blood sugar, vision changes, and depression or suicidal thoughts20.
Patients with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2 should not take Zepbound, as it may cause thyroid tumors20. Additionally, Zepbound has been associated with an increased risk of pancreatitis, prompting discontinuation and medical attention in case of severe abdominal pain21.
Despite these potential side effects, Zepbound has shown impressive weight loss results in clinical trials. Participants in the SURMOUNT-4 study who received the highest approved dosage of Zepbound (15 mg once weekly) lost an average of 20.9% of their body weight after 36 weeks of open-label treatment21. Moreover, the percentage of participants who maintained at least 80% of their weight loss during the lead-in period was significantly higher for Zepbound (93.4%) compared to placebo (13.5%)21.
It’s important for individuals considering Zepbound to discuss the potential risks and benefits with their healthcare provider. Proper monitoring and adherence to dosage instructions are crucial to ensure the safe and effective use of this weight loss medication22.
“Zepbound is a promising weight loss solution, but it’s essential to be aware of its potential side effects and work closely with a healthcare provider to ensure safe and effective use.”
Zepbound and Thyroid Cancer Risk
While Zepbound, a prescription medication approved for chronic weight management, has shown impressive results in clinical trials, it’s important to be aware of potential safety concerns. In studies with rats, Zepbound and similar medications were found to cause thyroid tumors, including thyroid cancer23. The occurrence rate of these thyroid tumors, including cancer, in humans using Zepbound is not yet fully clear23.
As a precautionary measure, Zepbound should not be used by patients with a personal or family history of medullary thyroid cancer or by those with Multiple Endocrine Neoplasia syndrome type 224. These conditions are associated with an increased risk of thyroid tumors, and the use of Zepbound may potentially exacerbate this risk24.
Zepbound’s Potential Thyroid Cancer Risks
The FDA has issued a boxed warning about the potential risk of thyroid cancer associated with Zepbound24. While serious side effects like thyroid cancer are not common, it’s crucial for healthcare providers and patients to be aware of this potential risk24.
Patients with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2 should avoid using Zepbound, as it may increase their risk of developing thyroid tumors24. It’s essential to have open discussions with healthcare providers about the risks and benefits of Zepbound, especially for individuals with a predisposition to thyroid conditions24.
In summary, while Zepbound can be an effective weight loss solution for many individuals, it’s crucial to understand the potential risks, particularly regarding thyroid cancer. Patients with specific medical histories should exercise caution and consult with their healthcare providers to determine the most appropriate course of action2324.
Precautions and Contraindications
When it comes to the weight loss medication Zepbound, it’s important to be aware of certain precautions and contraindications25. For instance, Zepbound should not be used in combination with Mounjaro or any other GLP-1 receptor agonist, as the safety and effectiveness of using Zepbound with other weight management medications have not been established25. Additionally, Zepbound should not be used in patients with a history of severe allergic reaction to tirzepatide or any of its other ingredients25.
Patients should stop taking Zepbound immediately and seek medical help if they experience symptoms of a severe allergic reaction, such as difficulty breathing, swelling of the face, lips, tongue, or throat25. Furthermore, Zepbound is not recommended for use in patients with a history of pancreatitis or severe gastrointestinal disease, as it has not been studied in these populations25.
It’s also important to note that Zepbound may increase the risk of thyroid tumors, and pregnant women should avoid using it as it can harm the unborn baby25. Women using birth control pills may need to switch to another form of birth control while taking Zepbound25.
Potential side effects of Zepbound include gaseous stomach pain, indigestion, severe nausea, and yellowing of the skin25. Zepbound may also cause diabetic retinopathy, leading to blurred vision, and low blood sugar when used with other medications25. Symptoms of low blood sugar while taking Zepbound include anxiety, blurred vision, excessive hunger, and shakiness25.
In some cases, Zepbound can lead to behavioral changes, agitation, and even suicidal thoughts25. Acute kidney injury may also be a side effect, presenting with symptoms such as bloody urine and swelling25. It’s essential for patients to be aware of these potential risks and to follow their healthcare provider’s instructions carefully when using Zepbound25.
In conclusion, while Zepbound can be an effective weight loss solution, it’s crucial to understand the precautions and contraindications associated with its use25. Patients should work closely with their healthcare providers to ensure they are using Zepbound safely and effectively25.
Weight Loss with Lifestyle Changes
While the weight loss medication Zepbound has demonstrated impressive results in clinical trials2627, it is important to note that the medication is intended to be used in conjunction with a reduced-calorie diet and increased physical activity. Adopting healthy lifestyle habits is essential for achieving and maintaining weight loss when taking Zepbound.
Lifestyle changes, such as following a balanced diet and engaging in regular exercise, play a crucial role in maximizing the weight loss benefits of Zepbound28. Studies have shown that lifestyle modifications can significantly reduce the incidence of obesity-related conditions like coronary artery disease and type 2 diabetes28.
- Patients should work closely with their healthcare providers to develop a comprehensive weight management plan that integrates both medical treatment and lifestyle modifications.
- Zepbound users are advised to follow a balanced diet and an exercise routine consisting of at least 150 minutes of physical activity per week to maximize weight loss results27.
- Adopting healthy habits, such as mindful eating, regular physical activity, and stress management, can enhance the effectiveness of Zepbound and support long-term weight loss28.
By incorporating lifestyle changes alongside Zepbound treatment, individuals can achieve more significant and sustainable weight loss outcomes2627. Healthcare providers play a crucial role in guiding patients through this comprehensive approach to weight management.
| Metric | Zepbound Users | Placebo Group |
|---|---|---|
| Average Weight Loss | 15-20% of body weight27 | 5 pounds27 |
| Waistline Reduction | 5.5-7.3 inches27 | N/A |
| Body Fat Reduction | Nearly 34%27 | N/A |
By combining Zepbound with a comprehensive lifestyle approach, individuals can achieve more significant and sustainable weight loss results2627.
“Lifestyle changes focusing on healthy habits like diet, physical activity, and stress management can reduce the incidence of coronary artery disease by over 80% and Type 2 diabetes by more than 90%.”28
The key to long-term weight management lies in the integration of medical treatment and lifestyle modifications262827. By working closely with their healthcare providers, individuals can develop a personalized plan that leverages the power of Zepbound and healthy lifestyle changes to achieve their weight loss goals262827.
Priority Review and Fast Track Designations
Zepbound, the prescription medication approved by the FDA for chronic weight management, received two significant designations that helped expedite its development and review process – Priority Review and Fast Track designations29. These designations are intended to accelerate the approval of drugs that address serious conditions and unmet medical needs, like the obesity epidemic that affects nearly 70% of American adults30.
The Priority Review designation from the FDA meant that the agency committed to reviewing Zepbound’s new drug application in a shorter timeframe, aiming to make the medication available to patients more quickly29. The Fast Track designation further facilitated the development and review of Zepbound, allowing for more frequent communication between the FDA and the drug’s manufacturer, Eli Lilly, to ensure efficient progress29.
Zepbound’s impressive clinical trial results, which demonstrated significant weight loss in both individuals with and without diabetes, were key factors in the FDA’s decision to grant these special designations3029. The drug is anticipated to be available in the U.S. by the end of 2023, offering a new and effective option for the millions of Americans struggling with obesity and overweight conditions30.
Analysts project that Zepbound could generate up to $48 billion in annual sales by 2030, as it presents a competitive and potentially transformative solution for chronic weight management31. With the Priority Review and Fast Track designations, Zepbound’s path to market has been accelerated, providing hope for those seeking an effective weight loss treatment3129.
“Zepbound’s approval, with its impressive weight loss results, represents an important advancement in the fight against the growing obesity epidemic. The Priority Review and Fast Track designations underscore the urgent need for new, effective weight management therapies.”
Conclusion
Zepbound, the brand name for the medication tirzepatide, has emerged as a promising solution for chronic weight management in adults with obesity or overweight with at least one weight-related condition. Clinical trials have demonstrated significant weight loss32 when Zepbound is used in combination with a reduced-calorie diet and increased physical activity.
Patients taking the highest approved dose of Zepbound (15 mg) lost an average of 22.5% of their body weight after 72 weeks32, while those on lower doses also experienced substantial weight reductions. The weight loss benefits were observed regardless of the duration of33, making Zepbound a viable option for individuals with long-term weight issues as well.
Zepbound has proven to be a significant breakthrough in chronic weight34, offering adults with obesity and obesity-related health conditions a substantial option to combat these conditions. While it is important to be aware of potential side effects and contraindications, the overall safety profile and effectiveness of Zepbound make it a valuable tool in the ongoing fight against the obesity epidemic.
FAQ
What is Zepbound?
Zepbound, also known as tirzepatide, is an injectable prescription medication recently approved by the FDA for chronic weight management in adults with obesity (BMI of 30 kg/m2 or greater) or overweight (BMI of 27 kg/m2 or greater) with at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol.
How does Zepbound work?
Zepbound is a dual agonist that activates two hormone receptors – GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide or gastric inhibitory polypeptide). By imitating the actions of these natural hormones, Zepbound helps regulate glucose and lipid metabolism, slows gastric emptying to make patients feel fuller for longer, and ultimately leads to weight loss for individuals struggling with chronic obesity.
How effective is Zepbound for weight loss?
In clinical trials, patients who received Zepbound at dosages of 5 mg, 10 mg, or 15 mg once weekly, in combination with a reduced-calorie diet and increased physical activity, experienced statistically significant reductions in body weight compared to those who received placebo injections. In the larger trial of adults without diabetes, those taking the highest approved dose of 15 mg once weekly lost an average of 18% of their body weight.
What is the dosage and administration of Zepbound?
Zepbound is administered as a weekly subcutaneous injection. The dosage must be increased over 4 to 20 weeks to reach the target maintenance doses of 5 mg, 10 mg, or 15 mg once weekly. The maximum approved dosage of Zepbound is 15 mg once weekly.
What are the weight loss results for individuals with type 2 diabetes?
In a separate clinical trial involving 958 adults with type 2 diabetes, those who received the highest approved dosage of Zepbound (15 mg once weekly) lost an average of 12% of their body weight compared to those who received a placebo.
What are the potential side effects of Zepbound?
Zepbound can cause side effects such as nausea, diarrhea, vomiting, constipation, abdominal discomfort and pain, injection site reactions, fatigue, hypersensitivity reactions, burping, hair loss, and gastroesophageal reflux disease. More severe side effects may include kidney problems, gallbladder issues, allergic reactions, low blood sugar, vision changes, and depression or suicidal thoughts.
Is there a risk of thyroid cancer with Zepbound?
Zepbound has been shown to cause thyroid C-cell tumors, including thyroid cancer, in animal studies with rats. It is unknown whether Zepbound can also cause thyroid tumors, including medullary thyroid carcinoma (MTC), in humans. As a precaution, Zepbound should not be used in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2, as these conditions are associated with an increased risk of thyroid tumors.
Are there any contraindications or precautions with Zepbound?
Zepbound should not be used in combination with Mounjaro or any other GLP-1 receptor agonist. The safety and effectiveness of using Zepbound with other weight management medications have not been established. Zepbound should also not be used in patients with a history of severe allergic reaction to tirzepatide or any of its other ingredients.
Is weight loss on Zepbound dependent on lifestyle changes?
While Zepbound has demonstrated significant weight loss results in clinical trials, the medication is indicated for use in combination with a reduced-calorie diet and increased physical activity. Adopting healthy lifestyle habits, such as following a balanced diet and engaging in regular exercise, are essential for achieving and maintaining weight loss when taking Zepbound.
Why did Zepbound receive Priority Review and Fast Track designations from the FDA?
Zepbound received Priority Review and Fast Track designations from the FDA, which are intended to expedite the development and review of drugs that treat serious conditions and address unmet medical needs. These designations were granted to Zepbound to help accelerate the approval process and make the medication available to patients more quickly.
Source Links
- FDA Approves New Medication for Chronic Weight Management
- What Is Zepbound? How It Works, Cost And More
- Zepbound: Dosage, side effects, uses, and more
- Zepbound – Medi-Weightloss
- What is Zepbound? Does this new weight loss drug work better than Wegovy and Ozempic? Will it cut costs?
- Zepbound for Weight Loss: Health Experts Answer 10 Common Questions
- What is Zepbound | Zepbound (tirzepatide)
- Zepbound For Weight Loss, How It Works And More | Klarity
- What to know about Zepbound, Eli Lilly’s new weight loss drug
- Zepbound for Weight Loss: Uses, Dosages, and Side Effects
- Zepbound dosage: Forms, strengths, how to use, and more
- Getting Patients Started: Dosing & Prescribing | Zepbound (tirzepatide)
- Zepbound for Weight Loss: Usage, Dosage, Side Effects
- What the results of Wegovy’s longest clinical trial yet show about weight loss, side effects and heart protection | CNN
- Lilly’s Zepbound™ (tirzepatide) achieved additional 6.7% weight loss following a 36-week open-label lead-in period, for a total mean weight loss of 26.0% from study entry over 88 weeks
- Amgen’s Novel Weight Loss Drug Shows Potential for Longer Lasting Effect With Less Frequent Dosing Than Wegovy, Zepbound
- Patients regain weight after stopping Eli Lilly’s Zepbound, study says
- Weight loss: Zepbound effective for obesity-related health conditions
- Tirzepatide Enhances Weight Loss with Sustained Treatment but Discontinuation Leads to Weight Regain
- Breakthrough in Weight Management: Zepbound’s FDA Approval
- Lilly’s Zepbound™ (tirzepatide) achieved additional 6.7% weight loss following a 36-week open-label lead-in period, for a total mean weight loss of 26.0% from study entry over 88 weeks | Eli Lilly and Company
- Your guide to Ozempic-inspired weight-loss drugs: What to know about Wegovy and Zepbound
- These highlights do not include all the information needed to use ZEPBOUND safely and effectively. See full prescribing information for ZEPBOUND.ZEPBOUND® (tirzepatide) Injection, for subcutaneous useInitial U.S. Approval: 2022
- Zepbound side effects: What they are and how to manage them
- Tirzepatide (Subcutaneous Route)
- Mounjaro and Zepbound are effective for long-term weight loss
- How Much Weight Can You Lose on Zepbound? | Ro
- Weight-loss drugs aren’t a magic bullet. Lifestyle changes are key to lasting health
- FDA Approves Tirzepatide (Zepbound) for Chronic Weight Management
- Breaking: FDA Approves Tirzepatide Injection for Chronic Weight Management in Obesity, Overweight
- Lilly to price tirzepatide for obesity competitively
- Slow Responders to Zepbound Achieve Meaningful Weight Loss Eventually
- Weight loss: Mounjaro, Zepbound can help people with long-term obesity
- Zepbound for Weight Loss: New Way of Losing Weight | Dr. Brandon Richland, MD
